The skin is the largest organ in the human body and serves as the primary barrier between the internal environment and the external world. It is of great importance that this barrier is robust and in good health, both for the maintenance of our physical appearance and for the preservation of our general health. Emollients are products that play a pivotal role in the protection of this barrier and the maintenance of healthy skin functions.

The role of 'Emollients Plus' in current literature;
Next Generation Emollient

As documented in scientific literature, Emollient Plus represents a novel advancement in emollient technology, integrating the beneficial properties of first-, second-, and third-generation emollients with a unique blend of bioactive ingredients. ⁶⁻⁷

Emollient Plus contains occlusive and humectant ingredients to maintain the moisture balance of the skin. The occlusive ingredients prevent water loss from the skin, while the humectant ingredients are hygroscopic and water-retaining. Additionally, Emollient Plus contains skin-identical lipids, including physiological lipids, in equimolar ratios (3 Ceramides, 1 Cholesterol, 1 Free Fatty Acid) to maintain normal skin functions.

Emollient Plus, also known as the “Next Generation Emollient,” offers additional benefits for dry skin through the use of special bio-active ingredients. It contributes to the natural moisture balance of dry skin, nourishing and powerfully moisturising the skin.. ²

References:

1. Galli E, et al. Consensus conference on clinical management of pediatric atopic dermatitis.Italian Journal of Pediatrics. 2016;42(1).

2. Chandan N, et al. A new era of moisturizers. Journal of Cosmetic Dermatology. 2021;20(8):2425–30.

3. Mawazi SM, et al. A review of moisturizers; history, preparation, characterization and applications. Cosmetics. 2022;9(3):61.

4. Elias PM. Optimizing emollient therapy for skin barrier repair in atopic dermatitis. Annals of Allergy, Asthma; Immunology. 2022;128(5):505–11.

5. Elias PM, et al. Moisturizers versus current and next-generation barrier repair therapy for the management of atopic dermatitis. Skin Pharmacology and Physiology. 2018;32(1):1–7.

6. Araviiskaia E, et al. The role of a novel generation of emollients, ‘emollients plus’, in atopic dermatitis. Clinical, Cosmetic and Investigational Dermatology. 2022; Volume 15:2705–19.

7. Zelenkova H, et al. Impact of daily use of emollient ‘plus’ on corticosteroid consumption in patients with atopic dermatitis: An open, randomized controlled study. Journal of the European Academy of Dermatology and Venereology. 2023;37(S5):27–34.

Emollient Generations

The composition of emollients has been refined over time, resulting in enhanced efficacy in maintaining dermal hydration. Consequently, emollients are categorised into three generations: First, Second and Third. The latest generation of emollients, which encompass all three generations and are further optimised, are now available for use. ¹


First Generation Emollients
²⁻³:

  • The product contains ingredients that are designed to lock moisture into the skin, including petrolatum, lanolin and mineral oil.
  • Suitable for individuals with dry skin.
 

Second Generation Emollients ³:

  • Humectant ingredients, including glycerin, urea and lactate, enhance the skin’s capacity to retain moisture.
  • Suitable for use on dry and sensitive skin.
 

Third Generation Emollients ⁴⁻⁵:

  • The composition of these substances includes physiological lipids, such as ceramides, cholesterol and free fatty acids, which facilitate the repair and reinforcement of the skin barrier.
  • Suitable for use on sensitive, atopic and eczematous skin. In order to be considered skin-identical, the product must contain an equimolar ratio of three parts ceramide, one part cholesterol and one part free fatty acid.
  • They are well tolerated by the skin.

molien® Emollient Plus, birinci, ikinci ve üçüncü nesil emolyenlerin tüm faydalarını bir araya getiren ve özel bio-aktif içeriklerle zenginleştirilmiş gelecek nesil bir emolyenttir.

 

Bu bio-aktif içerikler şunlardır;

FİZYOLOJİK LİPİDLER

Seramid 1

Kolesterol

Seramid 3

Seramid 6 ll

Serbest Yağ Asidi

BİO-AKTİF İÇERİKLER

Skualan

Shea Yağı

Fitosfingozin

Hyaluronik Asit

Linoleik Asit